Crossing at a ford occurs often in a man's lifetime. It means setting sail even though your friends stay in harbour, knowing the route, knowing the soundness of your ship and the favour of the day. Votes: 3Miyamoto Musashi
This is largely the methodology I've used throughout my career - that is, starting with a question as to what might be the properties of a set of compounds that could be invented which were unusual and unpredictable. Many times I've felt a bit like Columbus setting sail. Votes: 3Donald Cram
Twenty years from now you will be more disappointed by the things that you didn't do than by the ones you did do. So throw off the bowlines. Sail away from the safe harbor. Catch the trade winds in your sails. Explore. Dream. Discover. Votes: 6 H. Jackson Brown, Jr.